Berberine

Berberine is effective as a weight loss supplement. Studies have examined the effects on body weight. In a 12-week study in obese individuals, reported about 5 pounds of weight loss, on average. The participants also lost 3.6% of their body fat. The researchers believe that the weight loss is caused by improved function of fat-regulating hormones, such as insulin, adiponectin and leptin. Berberine also appears to inhibit the growth of fat cells at the molecular level. (5) (5.A) Berberine exhibits anti-inflammatory and antioxidant effects in animal and human studies[*]. It is also proven to reduce inflammation in humans, in part through the AMPK pathway and by improving the metabolism of glucose (sugar). (5.B) It also may inhibit the growth of fat cells and stimulate the conversion of white adipose tissue to brown adipose tissue, which improves metabolism and fat-burning. (5.B)